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Cilomilast (30 mg/kg
selective and cell permeable CBP bromodomain inhibitor
CAS Number: 1516896-09-5
inhibits migration and invasion
PBIT was used at 10-30 µM in vitro
6-Mercaptopurine Catalog No.:M8131-10 Cilomilast (30 mg/kgMercaptopurine is a thiopurine derivative antimetabolite with antineoplastic and immunosuppressive activities. Produced through the metabolism of mercaptopurine by hypoxanthine guanine phosphoribosyltransferase (HGPRT), mercaptopurine metabolites 6 thioguanosine 5' phosphate (6 thioGMP) and 6 thioinosine (T IMP) inhibit nucleotide interconversions and de novo purine synthesis, thereby blocking the formation of purine nucleotides and inhibiting DNA
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