I don't often run it in my brews here for you on CoolStuffInc.com outside of either burn or budget stuff, but it's better the faster your foe's curve, the better this is since there are a few turns of things cast this can kill like most one, two and three-drops and many early planeswalkers and Commanders too
In Magic life is a resource, and in commander we have a lot of it, and Id gladly pay life and delve cards away to cast Profane Transfusion, Exsanguinate, and Villainous Wealth for super cheap
Also, kudos for WotC on the design of these cards, because most of the spells are conditional spells
This is a great combo for maintaing board control in the mid-game, and will help you keep your hand healthy while you stall out your opponent
For this added cost, you get a ton more value, as Sephiroth can easily draw you a card upon entry
nasty good