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JNJ-39758979 dihydrochloride (10 mg/kg
CAS Number: 73360-56-2
Isoflavone lupiwighteone induces cytotoxic
InChi: InChI=1S/C19H15ClN4O2/c1-10-11(4-3-6-22-10)19(25)24-17-16-13(8-14(20)18(17)26-2)12-5-7-21-9-15(12)23-16/h3-9
against human leukemic B-cell precursors
ZLJ-6 Size:Contact [email protected] for quotation JNJ-39758979 dihydrochloride (10 mg/kgIC50: 0. 73, 0. 31, and 0. 99 M for COX 1, COX 2, and 5 LO, respectively ZLJ 6 is a dual inhibitor of COX and 5 lipoxygenase (5 LO). Cyclooxygenase (COX) is an enzyme that is responsible for formation of prostanoids, such as thromboxane and prostaglandins such as prostacyclin. 5 lipoxygenase (5 LO) is the major source of leukotrienes. In vitro: ZLJ 6 was identified as a potent inhibitor of cyclooxygenase in human whole blood. It also inhibited the