NVP-BHG712 Catalog No.:M7900-2 Smiles: CC(C)C1=CC=CC=C1CC1=CC(C(=O)NC2C=CC(=CC=2)S(=O)(=O)C2=CC=CC=C2C(C)(C)C)=C(O)C(O)=C1O

Smiles: CC(C)C1=CC=CC=C1CC1=CC(C(=O)NC2C=CC(=CC=2)S(=O)(=O)C2=CC=CC=C2C(C)(C)C)=C(O)C(O)=C1O

PubMed PMID: 25776529

AGK2 also suppresses the TNF-α and IL-6 production in the culturing splenocytes (TNF-α: 68

Functional proteomics strategy for validation of protein kinase inhibitors reveals new targets for a TBB-derived inhibitor of protein kinase CK2

Smiles: CN(C1C=CC(=CC=1)C(F)(F)F)S(=O)(=O)C1C=CC(=CC=1)C(=O)NC1=NC(=CS1)C1=CC=CC=N1

NVP-BHG712 Catalog No.:M7900-2 Smiles: CC(C)C1=CC=CC=C1CC1=CC(C(=O)NC2C=CC(=CC=2)S(=O)(=O)C2=CC=CC=C2C(C)(C)C)=C(O)C(O)=C1ONVP BHG712, also known as BHG 712, is a EphB4 kinase inhibitor and BCR ABL inhibitor. NVP BHG712, which inhibits EphB4 kinase activity in the low nanomolar range in cellular assays showed high selectivity for targeting the EphB4 kinase when profiled against other kinases in biochemical as well as in cell based assays. BHG 712 shows excellent pharmacokinetic properties and potently inhibits EphB4 autophosphorylation in tissues after oral