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Formula: C30H31F4N3O6S
Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders
colon and cecum (Colo-205
with the IC50 value of 78
3)4)15-19(26)16-27-22-7-5-6-21-20(22)12-13-24-21/h5-13
PROTAC BRD4 Degrader-14 cinimide sodium Formula: C30H31F4N3O6SPROTAC BRD4 Degrader 14 is a PROTAC connected by ligands for von Hippel Lindau and BRD4, with IC50s of 1. 8 nM and 1. 7 nM for BRD4 BD1 and BD2, respectively. PROTAC BRD4 Degrader 14 is capable of potently degrading the BRD4 protein in PC3 prostate cancer cells. Product information Molecular Weight: 1150. 27 Formula: C57H61F2N9O11S2 Chemical Name: 8 (3,5 difluoropyridin 2 yl) N (2 {3 hydroxy 5 [2 ({[(2S) 1 [(2S,4R) 4 hydroxy 2 ({[4 (4 methyl 1,3
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