MC-Val-Cit-PAB-duocarmycin iotensin 1/2 (1-7) amide synthesis and SAR analysis of

synthesis and SAR analysis of novel selective small molecule S1P4-R agonists based on a (2Z

IC50: 127 and 190 nM for enzyme and cell

InChi: InChI=1S/C18H21ClN2O4S/c1-18(2

for 4 days) treatment results in robust downregulation of GRP mRNA levels at 2

H2O : 50 mg/mL (76

MC-Val-Cit-PAB-duocarmycin iotensin 1/2 (1-7) amide synthesis and SAR analysis ofMC Val Cit PAB duocarmycin is a drug linker conjugate for ADC with potent antitumor activity by using duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC Val Cit PAB. Product information CAS Number: 2055896 98 3 Molecular Weight: 1019. 60 Formula: C54H65ClN9O9 Chemical Name: ({4 [(2S) 5 (carbamoylamino) 2 [(2S) 2 [6 (2,5 dioxo 2,5 dihydro 1H pyrrol 1 yl)hexanamido] 3 methylbutanamido]pentanamido]phenyl}methyl)[2 ({2