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77(5):997-1003
Solubility: DMSO 84 mg/mL (200
5 mg/mL group at 24
InChiKey: KHWCPNJRJCNVRI-UHFFFAOYSA-N
It also potently inhibits HDAC1
Bisindolylmaleimide I (GF109203X) - CAS# 133052-90-1 0012 77(5):997-1003Bisindolylmaleimide I (GF109203X), a potent and highly selective PCK inhibitor., CAS No. 133052 90 1, is a potent and highly selective PCK inhibitor. bisindolylmaleimide I(GF 109203X )inhibits PKC isozymes alpha, beta 1, beta 2, gamma, delta and epsilon in vitro . GF 109203X inhibited GSK 3 in vitro, when assayed either in cell lysates (IC(50) 360 nM or in GSK 3beta immunoprecipitates (IC(50) 170 nM derived from rat epididymal adipocytes. Pretreatment
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